La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs
The 5’terminal oligopyrimidine (5’TOP) motif is a cis-regulatory RNA element located immediately downstream of the 7-methylguanosine [m7G] cap of TOP mRNAs, which encode ribosomal proteins and translation factors. In eukaryotes, this motif coordinates the synchronous and stoichiometric expression of...
المؤلفون الرئيسيون: | Lahr, RM, Fonseca, BD, Ciotti, GE, Al-Ashtal, HA, Jia, J-J, Niklaus, MR, Blagden, SP, Alain, T, Berman, AJ |
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التنسيق: | Journal article |
منشور في: |
eLife Sciences Publications
2017
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مواد مشابهة
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La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs
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