Effect of epitope flanking residues on the presentation of N-terminal cytotoxic T lymphocyte epitopes.

We here demonstrate that placing two distinct influenza virus nucleoprotein epitopes at the N terminus of a cytosolic protein selectively blocks their presentation to specific cytotoxic T lymphocytes. The block is a cytosolic phenomenon, which can be overcome by distancing the epitope from the prote...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Gileadi, U, Gallimore, A, Van der Bruggen, P, Cerundolo, V
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 1999