PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions

PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions

Proliferating cell nuclear antigen (PCNA) is an essential cofactor for DNA replication and repair, recruiting multiple proteins to their sites of action. We examined the effects of the PCNA S228I mutation that causes PCNA-associated DNA repair disorder (PARD). Cells from individuals affected by PAR...

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Bibliographic Details
Main Authors:	Wilson, R, Biasutto, A, Wang, L, Fischer, R, Baple, E, Crosby, A, Mancini, E, Green, C
Format:	Journal article
Language:	English
Published:	Elsevier 2016

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