PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions

PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions

Proliferating cell nuclear antigen (PCNA) is an essential cofactor for DNA replication and repair, recruiting multiple proteins to their sites of action. We examined the effects of the PCNA S228I mutation that causes PCNA-associated DNA repair disorder (PARD). Cells from individuals affected by PAR...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Wilson, R, Biasutto, A, Wang, L, Fischer, R, Baple, E, Crosby, A, Mancini, E, Green, C
Format:	Journal article
Sprache:	English
Veröffentlicht:	Elsevier 2016

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