Cavitation-enhanced tumour-targeting virotherapy by ultrasound

<p>Systemic administration of adenovirus type 5 (Ad5) vectors for the treatment of cancer is limited by poor circulation kinetics and inefficient uptake from the bloodstream into tumours. This study reports a novel method for linkage of highly-PEGylated gold nanoparticles (AuPEG) to Ad5 by a s...

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Bibliographic Details
Main Author: Mo, S
Other Authors: Coussios, C
Format: Thesis
Language:English
Published: 2013
Subjects: