GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women.

OBJECTIVE: Lumbar disc degeneration (LDD) is a serious social and medical problem which has been shown to be highly heritable. It has similarities with peripheral joint osteoarthritis (OA) in terms of both epidemiology and pathologic processes. A few known genetic variants have been identified using...

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Bibliographic Details
Main Authors: Williams, F, Popham, M, Hart, D, de Schepper, E, Bierma-Zeinstra, S, Hofman, A, Uitterlinden, A, Arden, N, Cooper, C, Spector, T, Valdes, A, van Meurs, J
Format: Journal article
Language:English
Published: 2011