Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification.

Inhibitor of apoptosis-stimulating protein of p53 (iASPP) is the most ancient member of the ASPP family of proteins and an evolutionarily conserved inhibitor of p53. iASPP is also a binding partner and negative regulator of p65RelA. Because p65RelA and the p53 family members often have opposite effe...

Full description

Bibliographic Details
Main Authors: Notari, M, Hu, Y, Koch, S, Lu, M, Ratnayaka, I, Zhong, S, Baer, C, Pagotto, A, Goldin, R, Salter, V, Candi, E, Melino, G, Lu, X
Format: Journal article
Language:English
Published: 2011