Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension.
Heparan and chondroitin sulfate proteoglycans (HSPGs and CSPGs, respectively) regulate numerous cell surface signaling events, with typically opposite effects on cell function. CSPGs inhibit nerve regeneration through receptor protein tyrosine phosphatase sigma (RPTPσ). Here we report that RPTPσ act...
主要な著者: | Coles, C, Shen, Y, Tenney, A, Siebold, C, Sutton, G, Lu, W, Gallagher, J, Jones, E, Flanagan, J, Aricescu, A |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2011
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