Crystal structures and molecular interactions of risedronate and zoledronate with human farnesyl diphosphate synthase

Detaylı Bibliyografya
Asıl Yazarlar:	Kavanagh, K, Guo, K, Wu, X, Knapp, S, Ebetino, F, Dunford, J, Rogers, M, Russell, R, Oppermann, U
Materyal Türü:	Conference item
Baskı/Yayın Bilgisi:	2006

Human farnesyl diphosphate synthase (FDFS): Crystal structure and molecular interactions with Nnitrogen-containing bisphosphonates.
Yazar:: Kavanagh, K, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Investigations into the kinetic mechanism of inhibition of farnesyl diphosphate synthase by nitrogen containing bisphosphonates
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Human farnesyl diphosphate synthase crystal structures with active and inactive bisphosphonates
Yazar:: Evdokimov, A, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Molecular modeling comparison of nitrogen-containing bisphosphonates of varying potency co-crystalized in farnesyl diphosphate synthase
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Modeling of bisphosphonate binding to farnesyl diphosphate synthase
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Molecular modeling comparison of nitrogen-containing bisphosphonates of varying potency co-crystalized in farnesyl diphosphate synthase
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Molecular interactions of nitrogen-containing bisphosphonates within farnesyl diphosphate synthase
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Plasmodium falciparum parasites overexpressing farnesyl diphosphate synthase/geranylgeranyl diphosphate synthase are more resistant to risedronate
Yazar:: Heloisa B Gabriel, ve diğerleri
Baskı/Yayın Bilgisi: (2018-08-01)

Analysis of the kinetic mechanism of inhibition of Farnesyl Pyrophosphate Synthase by nitrogen containing bisphosphonates.
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Predicting the clinical potencies of bisphosphonates: Divergence of hydroxyapatite and farnesyl diphosphate synthase binding affinities
Yazar:: Xia, Z, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Stereochemical evidence of the mode of binding of nitrogen containing bisphosphonates in farnesyl diphosphate synthase
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Molecular modeling of the bisphosphonates (BPs) in farnesyl diphosphate (FPP) synthase. Proposed new mechanism of inhibition by potent nitrogen containing bisphosphonates (NBPs).
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Molecular modeling of the bisphosphonates in farnesyl diphosphate synthase. potential new details of the precise biochemical mechanism of action of potent nitrogen containing bisphosphonates
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Kinetic analysis of conformational changes in farnesyl pyrophosphate synthase induced by nitrogen containing bisphosphonates
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Nitrogen-containing bisphosphonates of varying antiresorptive potency have been co-crystallized in farnesyl diphosphate synthase and modelled to understand the key structural features involved in enzyme inhibition.
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Structure activity relationships of nitrogen containing bisphosphonates which induce conformational changes in farnesyl pyrophosphate synthase
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Kinetic analysis of conformational changes in farnesyl pyrophosphate synthase induced by nitrogen containing bisphosphonates
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness
Yazar:: Hee Yeon Kim, ve diğerleri
Baskı/Yayın Bilgisi: (2018-10-01)

Evidence for the involvement of the threonine 201 side-chain in the interaction of nitrogen-containing bisphosphonates with farnesyl pyrophosphate synthase
Yazar:: Kwassi, A, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Alendronate and ibandronate affect osteoclast formation and size differently from risedronate and zoledronate
Yazar:: Mabilleau, G, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

The interaction of sidechain nitrogen with active site threonine is not essential for inhibition of farnesyl pyrophosphate synthase by nitrogen containing bisphosphonates
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Refining structure activity relationships among nitrogen containing bisphosphonates: Dissociation of mineral binding affinity and inhibitory potency on farnesyl diphosphate synthase.
Yazar:: Xia, Z, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Interaction of the active site threonine 201 sidechain with the nitrogen of nttrogen-containing bisphosphonates is not essential for slow tight inhibition to farnesyl pyrophosphate synthase
Yazar:: Dunford, J, ve diğerleri
Baskı/Yayın Bilgisi: (2008)

Molecular characterization of ginseng farnesyl diphosphate synthase gene and its up-regulation by methyl jasmonate
Yazar:: O. T. Kim, ve diğerleri
Baskı/Yayın Bilgisi: (2010-03-01)

Polyprenol formation in the yeast Saccharomyces cerevisiae: effect of farnesyl diphosphate synthase overexpression
Yazar:: A Szkopińska, ve diğerleri
Baskı/Yayın Bilgisi: (1997-05-01)

Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z‑Farnesyl Diphosphate Synthase
Yazar:: Yueh-Te Chan, ve diğerleri
Baskı/Yayın Bilgisi: (2017-03-01)

Functional characterization of a farnesyl diphosphate synthase from Dendrobium nobile Lindl
Yazar:: Daoyong Gong, ve diğerleri
Baskı/Yayın Bilgisi: (2022-10-01)

The mode of binding of nitrogen containing bisphosphonates in farnesyl pyrophosphate synthase
Yazar:: Ebetino, F, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Molecular cloning and characterization of farnesyl diphosphate synthase from Rosa rugosa Thunb associated with salinity stress
Yazar:: Guo Wei, ve diğerleri
Baskı/Yayın Bilgisi: (2024-02-01)

Functional characterization and transcriptional activity analysis of Dryopteris fragrans farnesyl diphosphate synthase genes
Yazar:: Dongrui Zhang, ve diğerleri
Baskı/Yayın Bilgisi: (2023-03-01)

Inhibitors of Farnesyl Diphosphate Synthase and Squalene Synthase: Potential Source for Anti-<i>Trypanosomatidae</i> Drug Discovery
Yazar:: Boniface Pone Kamdem, ve diğerleri
Baskı/Yayın Bilgisi: (2023-08-01)

Identification of a novel class of ω,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis
Yazar:: Rakesh K. Dhiman, ve diğerleri
Baskı/Yayın Bilgisi: (2004-06-01)

Designed mutants of human farnesyl pyrophosphate synthase (FPPS) help to characterise the interactions of nitrogen-containing bisphosphonates with Tyrosine 204 and Phenylalanine 239 side-chain residues
Yazar:: Tsoumpra, M, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

FARNESYL DIPHOSPHATE SYNTHASE (FDRS) AND GERANYLGERANYL DIPHOSPHATE SYNTHASE (GGSP1) GENE POLYMORPHISMS AND EFFICIENCY OF THERAPY WITH BISPHOSPHONATES IN RUSSIAN WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS: A PILOT STUDY
Yazar:: M. Yu. Krylov, ve diğerleri
Baskı/Yayın Bilgisi: (2016-03-01)

The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
Yazar:: Tsoumpra, M, ve diğerleri
Baskı/Yayın Bilgisi: (2015)

Insights about the structure of farnesyl diphosphate synthase (FPPS) and the activity of bisphosphonates on the proliferation and ultrastructure of Leishmania and Giardia
Yazar:: Ana Paula R. Gadelha, ve diğerleri
Baskı/Yayın Bilgisi: (2020-04-01)

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.
Yazar:: Kavanagh, K, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants
Yazar:: Tsoumpra, MK, ve diğerleri
Baskı/Yayın Bilgisi: (2015)

Crystal structures and molecular interactions of risedronate and zoledronate with human farnesyl diphosphate synthase

Benzer Materyaller

Benzer Materyaller