Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension.

It is well established that gene interactions influence common human diseases, but to date linkage studies have been constrained to searching for single genes across the genome. We applied a novel approach to uncover significant gene-gene interactions in a systematic two-dimensional (2D) genome-scan...

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Bibliographic Details
Main Authors: Bell, J, Wallace, C, Dobson, R, Wiltshire, S, Mein, C, Pembroke, J, Brown, M, Clayton, D, Samani, N, Dominiczak, A, Webster, J, Lathrop, G, Connell, J, Munroe, P, Caulfield, M, Farrall, M
Format: Journal article
Language:English
Published: 2006