Human T-cell leukemia virus type 1 envelope glycoprotein gp46 interacts with cell surface heparan sulfate proteoglycans.

The major receptors required for attachment and entry of the human T-cell leukemia virus type 1 (HTLV-1) remain to be identified. Here we demonstrate that a functional, soluble form of the HTLV-1 surface envelope glycoprotein, gp46, fused to an immunoglobulin Fc region (gp46-Fc) binds to heparan sul...

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Bibliographic Details
Main Authors: Piñon, J, Klasse, P, Jassal, SR, Welson, S, Weber, J, Brighty, D, Sattentau, Q
Format: Journal article
Language:English
Published: 2003