Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer.

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer.

Uterine leiomyomata (fibroids) are common and clinically important tumors, but little is known about their etiology and pathogenesis. We previously mapped a gene that predisposes to multiple fibroids, cutaneous leiomyomata and renal cell carcinoma to chromosome 1q42.3-q43 (refs 4-6). Here we show, t...

書誌詳細
主要な著者:	Tomlinson, I, Alam, N, Rowan, A, Barclay, E, Jaeger, E, Kelsell, D, Leigh, I, Gorman, P, Lamlum, H, Rahman, S, Roylance, R, Olpin, S, Bevan, S, Barker, K, Hearle, N, Houlston, R, Kiuru, M, Lehtonen, R, Karhu, A, Vilkki, S, Laiho, P, Eklund, C, Vierimaa, O, Aittomäki, K, Hietala, M
フォーマット:	Journal article
言語:	English
出版事項:	2002

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