Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis.

OBJECTIVE: To assess the role of the activating receptor NKG2D in arthritis. METHODS: Levels of NKG2D and its ligands were determined by fluorescence-activated cell sorting, real-time polymerase chain reaction, and immunohistochemistry in rheumatoid arthritis (RA) synovial membrane tissue and in pa...

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Bibliographic Details
Main Authors: Andersson, A, Sumariwalla, P, McCann, F, Amjadi, P, Chang, C, McNamee, K, Tornehave, D, Haase, C, Agersø, H, Stennicke, V, Ahern, D, Ursø, B, Trowsdale, J, Feldmann, M, Brennan, F
Format: Journal article
Language:English
Published: 2011