Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart.
The CAMPATH-1 family of antibodies are able systematically to lyse human lymphocytes with human complement by targeting the small cell-surface glycoprotein CD52, commonly called the CAMPATH-1 antigen. These antibodies have been used clinically for several years, providing therapy for patients with a...
Príomhchruthaitheoirí: | Cheetham, G, Hale, G, Waldmann, H, Bloomer, A |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
1998
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Míreanna comhchosúla
Míreanna comhchosúla
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1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.
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Rat monoclonal antibodies for bone marrow transplantation--the CAMPATH series.
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