Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart.
The CAMPATH-1 family of antibodies are able systematically to lyse human lymphocytes with human complement by targeting the small cell-surface glycoprotein CD52, commonly called the CAMPATH-1 antigen. These antibodies have been used clinically for several years, providing therapy for patients with a...
Հիմնական հեղինակներ: | Cheetham, G, Hale, G, Waldmann, H, Bloomer, A |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
1998
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Նմանատիպ նյութեր
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1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.
: James, L, և այլն
Հրապարակվել է: (1999) -
The CAMPATH-1 antigen (CDw52).
: Hale, G, և այլն
Հրապարակվել է: (1990) -
Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G.
: Williams, R, և այլն
Հրապարակվել է: (2000) -
Anti-globulin responses to rat and humanized CAMPATH-1 monoclonal antibody used to treat transplant rejection.
: Rebello, P, և այլն
Հրապարակվել է: (1999) -
Rat monoclonal antibodies for bone marrow transplantation--the CAMPATH series.
: Waldmann, H, և այլն
Հրապարակվել է: (1985)