Structure and substrate specificity of the Pim-1 kinase

Structure and substrate specificity of the Pim-1 kinase

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The Pim kinases are a family of three vertebrate protein serine/threonine kinases (Pim-1, -2, and -3) belonging to the CAMK (calmodulin-dependent protein kinase-related) group. Pim kinases are emerging as important mediators of cytokine signaling pathways in hematopoietic cells, and they contribute...

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Bibliographic Details
Main Authors: Bullock, A, Debreczeni, J, Amos, A, Knapp, S, Turk, B
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2005
Subjects:
Protein Binding
Arginine
Phosphorylation
Proto-Oncogene Proteins c-pim-1
Models, Molecular
Crystallography, X-Ray
Glycine
Peptide Library
Substrate Specificity
Hematopoietic Stem Cells
Cell Nucleus
Protein-Serine-Threonine Kinases
Protein Conformation
Amino Acid Motifs
physiology
Kinetics
Calorimetry
metabolism
Binding Sites
Protein Isoforms
Calcium-Calmodulin-Dependent Protein Kinases
Humans
chemistry
Peptide Nucleic Acids
Cytoplasm
Proto-Oncogene Proteins
Biotinylation
Calcium-Calmodulin-Dependent Protein Kinase Type 1
Protein Structure, Tertiary
Peptides

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