Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.

BACKGROUND: Copy number variants (CNVs) are a major form of genomic variation, which may be implicated in complex disease phenotypes. However, investigation of the role of CNVs in coronary heart disease (CHD) traits has been limited. METHODS AND RESULTS: We examined the use of the cnvHap algorithm f...

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Bibliographic Details
Main Authors: Costelloe, S, El-Sayed Moustafa, J, Drenos, F, Palmen, J, Li, Q, Qiao, L, Whiting, S, Thomas, M, Kivimaki, M, Kumari, M, Hingorani, A, Tzoulaki, I, Järvelin, MR, Marjo-Riitta, J, Ruokonen, A, Aimo, R, Hartikainen, A, Pouta, A, Walters, R, Blakemore, A, Humphries, SE, Coin, L, Talmud, P
Format: Journal article
Language:English
Published: 2012