Xenon plasma focused ion beam lamella fabrication on high-pressure frozen specimens for structural cell biology

Cryo focused ion beam lamella preparation is a potent tool for in situ structural biology, enabling the study of macromolecules in their native cellular environments. However, throughput is currently limited, especially for thicker, more biologically complex samples. We describe how xenon plasma foc...

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Bibliographic Details
Main Authors: Berger, C, Watson, H, Naismith, JH, Dumoux, M, Grange, M
Format: Journal article
Language:English
Published: Nature Research 2025