The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists.

The discovery of a novel series of 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamide antagonists of the vasopressin V(1A) receptor is disclosed. Compounds 47 and 48 were found to be high affinity, selective vasopressin V(1A) antagonists.

Bibliographic Details
Main Authors:	Napier, S, Wishart, G, Arbuckle, W, Baker, J, Barn, D, Bingham, M, Brown, A, Byford, A, Claxton, C, Craighead, M, Buchanan, K, Fielding, L, Gibson, L, Goodwin, R, Goutcher, S, Irving, N, MacSweeney, C, Milne, R, Mort, C, Presland, J, Sloan, H, Thomson, F, Turnbull, Z, Young, T
Format:	Journal article
Language:	English
Published:	2011

The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists.

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