Biologically-informed neural networks guide mechanistic modeling from sparse experimental data

Biologically-informed neural networks (BINNs), an extension of physics-informed neural networks [1], are introduced and used to discover the underlying dynamics of biological systems from sparse experimental data. In the present work, BINNs are trained in a supervised learning framework to approxima...

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Bibliographic Details
Main Authors: Lagergren, JH, Nardini, JT, Baker, RE, Simpson, MJ, Flores, KB
Format: Journal article
Language:English
Published: Public Library of Science 2020