Selective culture enrichment and sequencing of feces to enhance detection of antimicrobial resistance genes in third-generation cephalosporin resistant Enterobacteriaceae

Metagenomic sequencing of fecal DNA can usefully characterise an individual’s intestinal resistome but is limited by its inability to detect important pathogens that may be present at low abundance, such as carbapenemase or extended-spectrum beta-lactamase producing Enterobacteriaceae. Here we aimed...

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Bibliographic Details
Main Authors: Peto, L, Fawcett, N, Crook, D, Peto, T, Llewelyn, M, Walker, A
Format: Journal article
Published: Public Library of Science 2019