Monitoring digoxin therapy: II. Determinants of the apparent volume of distribution.

1 In eighteen subjects receiving digoxin therapy the apparent volume of distribution (Vd) of the drug has been calculated. 2 For each subject the sensitivity of the 86Rb transport mechanism of his pre-treatment erythrocytes to in vitro inhibition by digoxin has been measured (IC50). 3 The Vd of digo...

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Bibliographic Details
Main Authors: Aronson, J, Grahame-Smith, D
Format: Journal article
Language:English
Published: 1977