Anti-TNFalpha therapy of rheumatoid arthritis: what can we learn about chronic disease?

The importance of tumour necrosis factor (TNF)alpha in rheumatoid arthritis (RA) was initially proposed on the basis of analysis of cytokine gene regulation at the local site of the disease, the synovium. This was then verified in animal models and established in an extensive series of clinical tria...

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Bibliographic Details
Main Authors: Feldmann, M, Brennan, F, Paleolog, E, Cope, A, Taylor, P, Williams, R, Woody, J, Maini, R
Format: Journal article
Language:English
Published: 2004