Humanization of an anti-mucin antibody for breast and ovarian cancer therapy.

Antibody-drug conjugates utilize the targetting potential of antibodies to improve the potential of cytostatic or cytocidal drugs. One such murine monoclonal antibody, CTM01 (mCTM01), which recognizes an epitope on breast epithelial mucin, has potential for the treatment of breast and ovarian cancer...

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Bibliographic Details
Main Authors: Baker, T, Bose, C, Caskey-Finney, H, King, D, Lawson, A, Lyons, A, Mountain, A, Owens, R, Rolfe, MR, Sehdev, M
Format: Journal article
Language:English
Published: 1994