The synthesis of membrane permeant derivatives of myo-inositol 1,4,5-trisphosphate

In order to enable the study of the intracellular second messenger d-myo-inositol 1,4,5-trisphosphate (InsP3) and its receptors (InsP3Rs), it has been desirable to develop protected derivatives of InsP3 that are able to enter the cell, upon extracellular application. The subsequent removal of the li...

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Bibliographic Details
Main Authors: Conway, S, Thuring, J, Andreu, S, Kvinlaug, B, Roderick, H, Bootman, MD, Holmes, AB
Format: Journal article
Language:English
Published: 2006