Combining personalized neoantigen vaccination with chemotherapy and anti-PD-1 to treat NSCLC

In this issue of Cancer Cell, Awad et al. report a phase 1b clinical trial combining a personalized vaccine NEO-PV-01 with chemotherapy and anti-PD-1 pembrolizumab in first-line metastatic non-squamous NSCLC. They demonstrate that this treatment regimen was well tolerated and induced neoantigen-spec...

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Bibliographic Details
Main Authors: Leung, CSK, Van den Eynde, BJ
Format: Journal article
Language:English
Published: Cell Press 2022