SRβ coordinates signal sequence release from SRP with ribosome binding to the translocon
Protein targeting to the endoplasmic reticulum (ER) membrane is regulated by three GTPases, the 54 kDa subunit of the signal recognition particle (SRP) and the α- and β-subunits of the SRP receptor (SR). Using a soluble form of SR and an XTP-binding mutant of SRβ, we show that SRβ is essential for p...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2001
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