Biophysical Studies of Oligonucleotides Containing Duplex Stabilising Modifications
<p>Chemically modified DNA and RNA probes have been used in numerous diagnostic (e.g. fluorogenic PCR and <em>in situ</em> hybridisation) and therapeutic (e.g. exon-skipping and antisense) applications to increase duplex stability and facilitate mismatch discrimination. There is a...
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| Format: | Thesis |
| Language: | English |
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2016
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