Axonal and oligodendrocyte-localized IgM and IgG deposits in MS lesions

Background: Recent findings support the important role of antibodies in multiple sclerosis (MS) physiopathology. Thus, local IgG synthesis is a hallmark of the disease, and intrathecal IgM synthesis associates with a poor disease outcome. Methodology: The aim of this study was to investigate the pre...

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Bibliographic Details
Main Authors: Sádaba, M, Tzartos, J, Paíno, C, García-Villanueva, M, Álvarez-Cermeño, J, Villar, L, Esiri, M
Format: Journal article
Language:English
Published: 2012