Axonal and oligodendrocyte-localized IgM and IgG deposits in MS lesions
Background: Recent findings support the important role of antibodies in multiple sclerosis (MS) physiopathology. Thus, local IgG synthesis is a hallmark of the disease, and intrathecal IgM synthesis associates with a poor disease outcome. Methodology: The aim of this study was to investigate the pre...
Main Authors: | Sádaba, M, Tzartos, J, Paíno, C, García-Villanueva, M, Álvarez-Cermeño, J, Villar, L, Esiri, M |
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Format: | Journal article |
Language: | English |
Published: |
2012
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