A randomized study comparing combined pneumococcal conjugate and polysaccharide vaccination schedules in adults.

BACKGROUND: The widely used 23-valent plain polysaccharide vaccine (23vP) has limited effectiveness, produces short-lived immune responses, and induces attenuated antibody production after subsequent challenge with pneumococcal vaccines. Our goal was to examine whether priming with the 7-valent pne...

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Bibliographic Details
Main Authors: Lazarus, R, Clutterbuck, E, Yu, L, Bowman, J, Bateman, E, Diggle, L, Angus, B, Peto, T, Beverley, P, Mant, D, Pollard, A
Format: Journal article
Language:English
Published: 2011