Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity

While the induction of a neutralizing antibody response against HIV remains a daunting goal, data from both natural infection and vaccine-induced immune responses suggest that it may be possible to induce antibodies with enhanced Fc effector activity and improved antiviral control via vaccination. H...

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Bibliographic Details
Main Authors: Ackerman, M, Crispin, M, Yu, X, Baruah, K, Boesch, A, Harvey, D, Dugast, A, Heizen, E, Ercan, A, Choi, I, Streeck, H, Nigrovic, P, Bailey-Kellogg, C, Scanlan, C, Alter, G
Format: Journal article
Language:English
Published: American Society for Clinical Investigation 2013