Chromosome silencing mechanisms in X-chromosome inactivation: unknown unknowns.
Fifty years ago, Mary Lyon hypothesised that one of the two X chromosomes in female mammalian cells is inactivated at random during early embryogenesis and that the inactive X is then stably maintained through all subsequent cell divisions. Although Lyon's hypothesis is now widely regarded as f...
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| Formato: | Journal article |
| Idioma: | English |
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2011
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