Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens.

Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens.

N-ethyl-N-nitrosourea (ENU) is a widely used mutagen in genotypic and phenotypic screens aimed at elucidating gene function. The high rate at which ENU induces point mutations raises the possibility that an observed phenotype may be to the result of another unidentified linked mutation. This article...

書誌詳細
主要な著者:	Keays, D, Clark, T, Flint, J
フォーマット:	Journal article
言語:	English
出版事項:	2006

類似資料

Mutational Analysis of N-Ethyl-N-Nitrosourea (ENU) in the Fission Yeast Schizosaccharomyces pombe
著者:: Rafael Hoyos-Manchado, 等
出版事項: (2020-03-01)

Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans
著者:: Omar A. Itani, 等
出版事項: (2016-02-01)

An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria.
著者:: Silayuv E Bongfen, 等
出版事項: (2012-01-01)

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models
著者:: Esapa, C, 等
出版事項: (2015)

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models.
著者:: Christopher T Esapa, 等
出版事項: (2015-01-01)

An N-ethyl-N-nitrosourea (ENU) mutagenized mouse model for autosomal dominant non-syndromic kyphoscoliosis due to vertebral fusion
著者:: Esapa, C, 等
出版事項: (2018)

N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis elegans 3′ Splice Site Function in Vivo
著者:: Omar A. Itani, 等
出版事項: (2016-06-01)

A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis
著者:: Esapa, C, 等
出版事項: (2012)

A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis.
著者:: Christopher T Esapa, 等
出版事項: (2012-01-01)

Mice with an N-ethyl-N-nitrosourea (ENU) induced Tyr209Asn mutation in natriuretic peptide receptor 3 (NPR3) provide a model for kyphosis associated with activation of the MAPK signaling pathway
著者:: Esapa, C, 等
出版事項: (2016)

Modulation of autoimmune diabetes by N-ethyl-N-nitrosourea- induced mutations in non-obese diabetic mice
著者:: Lucienne Chatenoud, 等
出版事項: (2022-06-01)

N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels
著者:: Hrabé de Angelis Martin, 等
出版事項: (2009-06-01)

EFFECT OF ETHYL METHANESULFONATE (EMS) AND N-NITROSE-N´-ETHYL UREA (ENU) ON CALLUS GROWTH OF COMMON BEAN
著者:: Diana Lilova SVETLEVA, 等
出版事項: (2005-07-01)

An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.
著者:: Bentley, L, 等
出版事項: (2014)

An N-ethyl-n-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess
著者:: Bentley, L, 等
出版事項: (2014)

Exposure to N-ethyl-N-nitrosourea in adult mice alters structural and functional integrity of neurogenic sites.
著者:: Vivian Capilla-Gonzalez, 等
出版事項: (2012-01-01)

Spontaneous inflammatory pain model from a mouse line with <it>N</it>-ethyl-<it>N</it>-nitrosourea mutagenesis
著者:: Chen Tsung-Chieh, 等
出版事項: (2012-05-01)

Vanillic acid protects mortality and toxicity induced by N-ethyl-N-nitrosourea in mice; in vivo model of chronic lymphocytic leukemia
著者:: Ahmad Salimi, 等
出版事項: (2024-06-01)

Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen <it>N</it>-ethyl-<it>N</it>-nitrosourea
著者:: Guo Lei, 等
出版事項: (2010-10-01)

N-ethyl-n-nitrosourea induced leukaemia in a mouse model through upregulation of vascular endothelial growth factor and evading apoptosis
著者:: Abdullahi, Aliyu, 等
出版事項: (2020)

N-ethyl-N-nitrosourea-induced adaptor protein 2 sigma subunit 1 ( Ap2s1 ) mutations establish Ap2s1 loss-of-function mice
著者:: Gorvin, C, 等
出版事項: (2017)

Effects of N-methyl-N-nitrosourea on seed germination of Stevia rebaudiana
著者:: Ahmad, Lyena Watty Zuraine, 等
出版事項: (2019)

An N-ethyl-N-Nitrosourea Mutagenesis Screen in Mice Reveals a Mutation in <i>Nuclear Respiratory Factor 1</i> (<i>Nrf1)</i> Altering the DNA Methylation State and Correct Embryonic Development
著者:: Maria Alba Sorolla, 等
出版事項: (2021-07-01)

Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database
著者:: Tao Wang, 等
出版事項: (2018-01-01)

Antimutagenic components in Spatholobus suberectus Dunn against N-methyl-N-nitrosourea
著者:: Keiko Inami, 等
出版事項: (2019-12-01)

Selection of functional EPHB2 genotypes from ENU mutated grass carp treated with GCRV
著者:: Meher un Nissa, 等
出版事項: (2021-07-01)

HSP70 cleavage-induced photoreceptor cell death caused by N-methyl-N-nitrosourea
著者:: Yoshiki Koriyama, 等
出版事項: (2016-01-01)

Genotoxic and chemopreventive potentials of ethanol leaves extract of Annona muricata on N-Ethyl-N-Nitrosourea-induced pro-leukaemia carcinogen in mice model by bone marrow micronucleus assay
著者:: Oluwaseyi Bamisaye, 等
出版事項: (2022-12-01)

Histopathological features of peripheral T-cell lymphoma in Sprague Dawley rats induced with N-methyl-N-nitrosourea
著者:: Al-Salih, Hutheyfa A. H., 等
出版事項: (2011)

Alteration of serum biochemical parameters and urinalysis in Sprague Dawley rats administered with N-methyl-N-nitrosourea
著者:: Hakimi, M. K., 等
出版事項: (2012)

Lycium barbarum glycopeptide (wolfberry extract) slows N-methyl-N-nitrosourea-induced degradation of photoreceptors
著者:: Qihang Kong, 等
出版事項: (2024-01-01)

Short-term carcinogenicity study of N-methyl-N-nitrosourea in FVB-Trp53 heterozygous mice.
著者:: Na-Won Kim, 等
出版事項: (2023-01-01)

Involvement of neuronal nitric oxide synthase in N-methyl-N-nitrosourea-induced retinal degeneration in mice
著者:: Yoshiki Koriyama, 等
出版事項: (2015-03-01)

N-methyl-N-nitrosourea induces zebrafish anomalous angiogenesis through Wnt/β-catenin pathway
著者:: Saifang Fu, 等
出版事項: (2022-07-01)

Preventive effect of Oenothera rosea on N-methyl-N-nitrosourea- (NMU) induced gastric cancer in rats
著者:: Almora-Pinedo Y, 等
出版事項: (2017-12-01)

Role of Oxidative Stress in Retinal Photoreceptor Cell Death in N-Methyl-N-nitrosourea–Treated Mice
著者:: Kazuhiro Tsuruma, 等
出版事項: (2012-01-01)

The reason for the amelioration of N-methyl-N-nitrosourea- induced retinitis pigmentosa in rats by hydrogen-rich saline
著者:: Wei-Ming Yan, 等
出版事項: (2017-10-01)

N-Ethyl-N-Nitrosourea Induced Leukaemia in a Mouse Model: Protective Effect of Icaritin via Inhibition of IL-6/JAK2/STAT3 Pathway Causes Apoptosis
著者:: Hou X, 等
出版事項: (2024-02-01)

ENU-induced phenovariance in mice: inferences from 587 mutations.
著者:: Arnold, C, 等
出版事項: (2012)

ENU-induced phenovariance in mice: inferences from 587 mutations
著者:: Arnold Carrie N, 等
出版事項: (2012-10-01)