Airway epithelial cells generate pro-inflammatory tenascin-C and small extracellular vesicles in response to TLR3 stimuli and rhinovirus infection

Viral infections are a common cause of asthma exacerbations, with human rhinoviruses (RV) the most common trigger. RV signals through a number of different receptors, including toll-like receptor (TLR)3. Tenascin-C (TN-C) is an immunomodulatory extracellular matrix protein present in high quantities...

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Detalles Bibliográficos
Autores principales: Mills, JT, Schwenzer, A, Marsh, EK, Edwards, MR, Sabroe, I, Midwood, KS, Parker, LC
Formato: Journal article
Lenguaje:English
Publicado: Frontiers Media 2019