Discovery of TNF-alpha as a therapeutic target in rheumatoid arthritis: preclinical and clinical studies.

The development of effective new treatments is greatly facilitated by the understanding of the mechanisms of disease. In rheumatoid arthritis, there has been progress in understanding its immunology, the HLA class II predisposition including the 'shared epitope' and more recently in unders...

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Bibliographic Details
Main Authors: Feldmann, M, Maini, R
Format: Journal article
Language:English
Published: 2002