Phospho‐regulation, nucleotide binding and ion access control in potassium‐chloride cotransporters

Phospho‐regulation, nucleotide binding and ion access control in potassium‐chloride cotransporters

Potassium‐coupled chloride transporters (KCCs) play crucial roles in regulating cell volume and intracellular chloride concentration. They are characteristically inhibited under isotonic conditions via phospho‐regulatory sites located within the cytoplasmic termini. Decreased inhibitory phosphorylat...

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Bibliographic Details
Main Authors: Chi, G, Ebenhoch, R, Man, H, Tang, H, Tremblay, LE, Reggiano, G, Qiu, X, Bohstedt, T, Liko, I, Almeida, FG, Garneau, AP, Wang, D, McKinley, G, Moreau, CP, Bountra, KD, Abrusci, P, Mukhopadhyay, SMM, Fernandez‐Cid, A, Slimani, S, Lavoie, JL, Burgess‐Brown, NA, Tehan, B, DiMaio, F, Jazayeri, A, Robinson, CV, Dürr, KL
Format: Journal article
Language:English
Published: EMBO Press 2021

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