Hybrid framework for the simulation of stochastic chemical kinetics

Stochasticity plays a fundamental role in various biochemical processes, such as cell regulatory networks and enzyme cascades. Isothermal, well-mixed systems can be modelled as Markov processes, typically simulated using the Gillespie Stochastic Simulation Algorithm (SSA) [26]. While easy to impleme...

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Bibliographic Details
Main Authors: Duncan, A, Erban, R, Zygalakis, K
Format: Journal article
Published: Elsevier 2016