SALMON: solvent accessibility, ligand binding, and mapping of ligand orientation by NMR spectroscopy.
Quinone oxidoreductase 2 (NQO2) binds the prodrug tretazicar (also known as CB1954, 5-(aziridin-1-yl)-2,4-dinitrobenzamide), which exhibits a profound antitumor effect in human cancers when administered together with caricotamide. X-ray structure determination allowed for two possible orientations o...
Հիմնական հեղինակներ: | Ludwig, C, Michiels, P, Wu, X, Kavanagh, K, Pilka, E, Jansson, A, Oppermann, U, Günther, U |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2008
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