Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen.
CAMPATH-1 antibodies recognise a unique molecule on human lymphocytes and are unusually efficient at causing cell lysis with homologous complement. They have been successfully used for lymphocyte depletion in vivo in a variety of diseases. The antigen is a small glycosylphosphatidylinositol (GPI)-an...
Hauptverfasser: | Xia, M, Hale, G, Waldmann, H |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
1993
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