Predicting the dynamics of antiviral cytotoxic T-cell memory in response to different stimuli: cell population structure and protective function.

This paper examines the numerical and functional consequences of various stimuli on antiviral CD8+ T-cell memory using a mathematical model. The model is based upon biological evidence from the murine model of infection with lymphocytic choriomeningitis virus (LCMV) that the phenotype of immunologic...

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Bibliographic Details
Main Authors: Bocharov, G, Klenerman, P, Ehl, S
Format: Journal article
Language:English
Published: 2001