A Plasmodium berghei sporozoite-based vaccination platform against human malaria

There is a pressing need for safe and highly effective Plasmodium falciparum (Pf) malaria vaccines. The circumsporozoite protein (CS), expressed on sporozoites and during early hepatic stages, is a leading target vaccine candidate, but clinical efficacy has been modest so far. Conversely, whole-spor...

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Bibliographic Details
Main Authors: Mendes, AM, Machado, M, Gonçalves-Rosa, N, Reuling, IJ, Foquet, L, Marques, C, Salman, AM, Yang, ASP, Moser, KA, Dwivedi, A, Hermsen, CC, Jiménez-Díaz, B, Viera, S, Santos, JM, Albuquerque, I, Bhatia, SN, Bial, J, Angulo-Barturen, I, Silva, JC, Leroux-Roels, G, Janse, CJ, Khan, SM, Mota, MM, Sauerwein, RW, Prudêncio, M
Format: Journal article
Published: Springer Nature 2018