Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo.

Malarial anemia is a global public health problem and is characterized by a low reticulocyte response in the presence of life-threatening hemolysis. Although cytokines, in particular tumor necrosis factor-alpha (TNF-alpha), can suppress erythropoiesis, the grossly abnormal bone marrow morphology ind...

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Main Authors: Casals-Pascual, C, Kai, O, Cheung, J, Williams, S, Lowe, B, Nyanoti, M, Williams, T, Maitland, K, Molyneux, M, Newton, C, Peshu, N, Watt, S, Roberts, D
格式: Journal article
语言:English
出版: 2006