α-Amino bicycloalkylation through organophotoredox catalysis †

Bridged bicycloalkanes such as bicyclo[1.1.1]pentanes (BCPs) and bicyclo[3.1.1]heptanes (BCHeps) are important motifs in contemporary drug design due to their potential to act as bioisosteres of disubstituted benzene rings, often resulting in compounds with improved physicochemical and pharmacokinet...

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Hlavní autoři: Nugent, J, López-Francés, A, Sterling, AJ, Tay, MY, Frank, N, Mousseau, JJ, Duarte, F, Anderson, EA
Médium: Journal article
Jazyk:English
Vydáno: Royal Society of Chemistry 2024