Mode of action and application of Scorpion primers to mutation detection.

Scorpion primers can be used to detect PCR products in homogeneous solution. Their structure promotes a unimolecular probing mechanism. We compare their performance with that of the same probe sequence forced to act in a bimolecular manner. The data suggest that Scorpions indeed probe by a unimolecu...

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Bibliographic Details
Main Authors: Thelwell, N, Millington, S, Solinas, A, Booth, J, Brown, T
Format: Journal article
Language:English
Published: 2000