Structural analyses on intermediates in serine protease catalysis.
Although the subject of many studies, detailed structural information on aspects of the catalytic cycle of serine proteases is lacking. Crystallographic analyses were performed in which an acyl-enzyme complex, formed from elastase and a peptide, was reacted with a series of nucleophilic dipeptides....
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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