An investigation into the mechanisms underpinning the pH-sensitivity of GLP-1 release from the enteroendocrine cells of the gut
GLP-1 is a gut hormone primarily secreted from the enteroendocrine L-cell in response to a meal. GLP-1 acts to potentiate insulin secretion from pancreatic beta-cells and suppress appetite through actions on POMC and NPY neurons in the PVN. Reports of a lower average gut pH in obese and diabetic pat...
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| Format: | Thesis |
| Language: | English |
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2023
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