Glucosidase inhibitors induce HCV glycoproteins misfolding, impair viral assembly and release, and reduce the infectivity of residually secreted HCV particles

Novel anti-HCV molecules are still needed to better combat HCV infection. Molecules targeting specifically viral activities are the most attractive in terms of drug development and are therefore the most studied. The antiviral properties of glucosidase inhibitors were established using the most rele...

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Bibliographic Details
Main Authors: Chapel, C, Garcia, C, Bartosch, B, Roingeard, P, Zitzmann, N, Cosset, F, Dubuisson, J, Dwek, R, Trepo, C, Zoulim, F, Durantel, D
Format: Conference item
Published: Wiley 2006