Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study.

BACKGROUND: Diagnosing drug-resistance remains an obstacle to the elimination of tuberculosis. Phenotypic drug-susceptibility testing is slow and expensive, and commercial genotypic assays screen only common resistance-determining mutations. We used whole-genome sequencing to characterise common and...

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Bibliographic Details
Main Authors:	Walker, T, Kohl, T, Omar, S, Hedge, J, Del Ojo Elias, C, Bradley, P, Iqbal, Z, Feuerriegel, S, Niehaus, K, Wilson, D, Clifton, D, Kapatai, G, Ip, C, Bowden, R, Drobniewski, F, Allix-Béguec, C, Gaudin, C, Parkhill, J, Diel, R, Supply, P, Crook, D, Smith, E, Walker, A, Ismail, N, Niemann, S, Peto, T
Format:	Journal article
Language:	English
Published:	Elsevier 2015

Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study.

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