Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification

<br/><strong>Objective: </strong>Pathological Wnt pathway activation is a conserved hallmark of colorectal cancer. Wnt-activating mutations can be divided into: i) ligand-independent (LI) alterations in intracellular signal transduction proteins (Adenomatous polyposis coli, β-caten...

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Bibliographic Details
Main Authors: Kleeman, S, Koelzar, V, Jones, HJS, Vazquez, E, Davis, H, East, JE, Arnold, R, Koppens, MAJ, Blake, A, Domingo, E, Cunningham, C, Beggs, AD, Pestinger, V, Loughrey, MB, Wang, L-M, Lannagan, TRM, Woods, SL, Worthley, D, Tomlinson, I, Dunne, PD, Maughan, T, Leedham, SJ
Format: Journal article
Published: BMJ Publishing Group 2019