Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification
<br/><strong>Objective: </strong>Pathological Wnt pathway activation is a conserved hallmark of colorectal cancer. Wnt-activating mutations can be divided into: i) ligand-independent (LI) alterations in intracellular signal transduction proteins (Adenomatous polyposis coli, β-caten...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Journal article |
Published: |
BMJ Publishing Group
2019
|